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Postdoctoral Researcher in Peter MacCallum Cancer Centre

  • Australia
  • Posted 2 years ago
  • Applications have closed

Peter Mac

Deadline: May 8, 2023

At Peter Mac we aim to continuously improve cancer care, research and education across all cancers and for all people affected by cancer: changing lives, breaking new ground. Everything we do is underpinned by our core values, Excellence, Compassion and Innovation. Welcoming people from a wide variety of different backgrounds and experiences is critical to fostering innovation, cultivating compassion, attracting and retaining top talent and providing the best possible cancer care for our patients.

YOUR ROLE IN OUR FUTURE

Post-Doctoral Researcher x2 – Parker Laboratory

We require two full-time postdoctoral researchers who will fill an exciting new role leading translational cancer projects in the Parker laboratory. The role will directly contribute to projects centred around personalised immune-based and targeted therapies for prostate and breast cancer, with a particular focus on targeting bone metastases by increasing cancer cell immunogenicity. The laboratories rely heavily on patient metastatic tissue and novel preclinical models including patient-derived and metastatic mouse models of cancer, coupled with therapeutic screening and biomarker discovery. There is a strong emphasis on clinical collaborations and active clinical trials to translate results from the laboratory bench to the patient bedside.

The successful applicants will play a key senior role in the laboratory, closely working with the Laboratory Head Assoc Prof Belinda Parker managing projects recently funded by NBCF and NHMRC. Key experiments to conduct/oversee will include implementation of preclinical models, including cell culture, patient tissue organoid establishment and mouse experiments. They will play a critical role in maintaining associated databases and records to facilitate preclinical research projects in the laboratory and be exposed to a broad range of techniques including animal modelling, bone imaging (including multiphoton), patient cell line derivation, histology (including Opal mIHC and spatial technologies) and tumour immunology protocols.

Examples of work conducted by Assoc Prof Parker that exemplify the efforts and translational capacity of her laboratory can be found in the publications: Brockwell et al npj Precision Oncology 2019, Bidwell et al 2012 Nature Medicine, Owen et al EMBO rep 2020, and Balaur et al Nature 2021. The candidate must hold a PhD in a relevant discipline (preferably in Oncology) and have expertise in models of breast and/or prostate cancer. Exceptional communication skills, time management skills, and attention to detail are a must. Technical precision whilst carrying out experiments is also critical. Further to this, you must be an effective project leader who can dynamically problem solve whilst maintaining a safe and effective working environment.

Applicants to this role should provide a covering letter outlining relative key skills and experience to assist us with our assessment.

For further information about this opportunity, click Apply to be redirected to the Peter Mac Careers page where you can review the position summary.

Alternatively, please contact us using the information below for a confidential discussion.

Hiring Manager: A/Prof Belinda Parker
Email: belinda.parker@petermac.org

Applications Close: 11:59 pm 8 May 2023
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Position Summary

We require two full-time postdoctoral researchers who will fill an exciting new role leading translational cancer projects in the Parker laboratory. The role will directly contribute to projects centred around personalised immune-based and targeted therapies for prostate and breast cancer, with a particular focus on targeting bone metastases by increasing cancer cell immunogenicity. The laboratories rely heavily on patient metastatic tissue and novel preclinical models including patient-derived and metastatic mouse models of cancer, coupled with therapeutic screening and biomarker discovery. There is a strong emphasis on clinical collaborations and active clinical trials to translate results from the laboratory bench to the patient bedside.

The successful applicants will play a key senior role in the laboratory, closely working with the Laboratory Head Assoc Prof Belinda Parker managing projects recently funded by NBCF and NHMRC.  Key experiments to conduct/oversee will include implementation of preclinical models, including cell culture, patient tissue organoid establishment and mouse experiments. They will play a critical role in maintaining associated databases and records to facilitate preclinical research projects in the laboratory and be exposed to a broad range of techniques including animal modelling, bone imaging (including multiphoton), patient cell line derivation, histology (including Opal mIHC and spatial technologies) and tumour immunology protocols. Examples of work conducted by Assoc Prof Parker that exemplify the efforts and translational capacity of her laboratory can be found in the publications: Brockwell et al npj Precision Oncology 2019, Bidwell et al 2012 Nature Medicine, Owen et al EMBO rep 2020, and Balaur et al Nature 2021. The candidate must hold a PhD in a relevant discipline (preferably in Oncology) and have expertise in models of breast and/or prostate cancer. Exceptional communication skills, time management skills, and attention to detail are a must. Technical precision whilst carrying out experiments is also critical. Further to this, you must be an effective project leader who can dynamically problem solve whilst maintaining a safe and effective working environment.

Enterprise Agreement

Allied Health Professionals (Victorian Public Sector) (Single interest employers) Enterprise Agreement 2021 – 2026

Classification or Salary Range

1RA7 – 1RA10

Immunisation Risk Category

Category A: Position involving direct patient contact, potential for exposure to blood, body fluid, human tissue specimens during course of a normal working day

Key Relationships

Internal:
•    A/Prof Belinda Parker (Group Leader) and members of the Parker lab
•    Staff members of Research Core Facilities
•    Cancer Research Division staff and students

External:
•    Staff and students from other research institutes
•    Funding bodies
•    Consumers

Skills

Essential Requirements:
•    Completion of a PhD in the relevant discipline, and evidence of participation in higher level study relevant to discipline or professional area.
•    Evidence of experience in research and evaluation and the ability to work effectively under limited supervision or independently
•    Experience in leadership and/or supervision of projects and research staff/students
•    Experience in working with animal models of cancer, preferably breast and/or prostate cancer, and previous experience with contributing to ethics applications/reporting
•    Experience with molecular biology and immunology techniques including Flow cytometry, ELISA, tissue culture, real time PCR
•    Experience in microscopy, including IF and IHC
•    A record of contribution to publications, conference papers and/or reports, or professional or technical contributions which provide evidence of research potential
•    Effective oral and written communication skills, including the ability to interact effectively with people from a diverse range of backgrounds
•    Demonstrated ability to work as a member of a team in a cooperative and collegial manner
•    Demonstrated high level of self-motivation and personal management skills
•    A passion for translational science

Desirable Requirements:
•    Experience in mIHC and multiphoton imaging
•    Experience in the preparation of research proposal submissions to external funding bodies and evidence of success in securing research funding

Key Accountabilities

1. Performing experiments to a high standard •    Careful and precise experimental technique
•    Accurate analysis and interpretation of data
•    Ability to follow and understand instructions
•    Willingness to learn
•    Ability to work with limited supervision
•    Careful, accurate and timely record keeping
•    Follow guidelines for systematic data storage
•    High level of integrity and ethics
•    Hard working with high level work ethic
2. Communication of research outcomes •    Conduct and publish, or otherwise disseminate high quality and/or high impact research/scholarly activities under limited supervision either independently or as part of a team
•    Contribute to writing up research findings for publication and dissemination
•    Assist in obtaining research funding from external sources
•    Participate in professional activities including presentations at conferences and seminars in field of expertise
•    Provide advice within the field of the employee’s research to Honours and postgraduate students
•    Attendance at meetings associated with research or the work of the unit to which the research is connected
•    Acquire and interpret research data and results. Run analyses and tests using specified and agreed techniques and models. Contribute to the development of techniques, models and methods.
3. Foster a good working relationship with colleagues •    Development of good working relationships with others both within the laboratory and within the Research Division
•    Demonstrated ability to work as part of a research team
•    Ability to work closely with lab head to manage the team
•    Help with general laboratory maintenance and undertaking fair share of laboratory chores
•    Assistance to others in the lab when needed
•    Undertake other duties commensurate with the classification and scope of the position as required.
4. Training of junior staff/students •    Teaching of relevant techniques to new staff
•    Accurate recording of protocols to ensure reproducibility of experiments
5. Abides by OHS requirements •    Complies with Infection Control policies and procedures 100% of the time
•    Completes incident reports 100% of the time and responds appropriately to OH&S incidents
•    Attends Health & Safety training on emergency procedures annually and is capable of identifying emergency equipment in place
•    Follows established procedures

_____________________________________________________________________________________________________

For further information about this opportunity, click Apply to be redirected to the Peter Mac Careers page where you can review the position profile. Alternatively, please contact us for a confidential discussion.

Peter Mac requires its staff to be fully vaccinated against COVID-19. Please contact us if you would like to discuss this requirement.

WHY WORK FOR PETER MAC

  • Peter Mac offer a range of benefits which support our people both personally and professionally.
  • Our staff benefits include award winning facilities, professional development and events, a health and wellbeing program, flexible work practices and policies and financial benefits such as salary packaging.
  • We encourage applications from Aboriginal and Torres Strait Islander people, all members of the LGBTQI community and people with a disability.

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