YOUR MISSION
The Buschbeck lab is looking for a motivated junior researcher to join them at the IJC head-quarters in Badalona for a 6-12 month training period with the option to continue as a PhD student.
Research Description
Intrinsic and acquired resistances are the main reason for failure of current cancer treatments. Even for the best available treatments, initial responses are limited to less than 50% of patients and virtually all responders eventually relapse and progress. The best solution to avoid and overcome resistances is the combination of multiple drugs attacking the disease from different angles.
We are looking for someone who would like to address this exciting and highly relevant problem in the context of hematologic malignancies. We will test histone variants and other chromatin regulators as potential drug targets.
The contract will be covered in parts by the Fundació La Marató de TV3, through the grant entitled ‘Explorant i explotant les variants d’histones com a dianes terapèutiques en la leucèmia mieloide aguda’ (Ref. No. 201907-30-31), the AECC through the grant entitled ‘Epigenetic re-education of the bone marrow stroma niche as a therapeutic approach for preventing blood cancer’ (PRYGN222668BUSC) and through the grant entitled ‘Enhancer regulation and nuclear metabolite sensing by histone variants’ (Ref. number PID2021-126907NB-I00) funded by the Spanish National Research Agency AEI and FEDER, UE.
For more info about the lab please check out our website: https://www.buschbecklab.org
Main responsabilities
- Cell culture, genetic and pharmacologic perturbations.
- Molecular biology.
- Basic biochemistry.
- Data analysis and interpretation.
- Report writing.