PhD Positions in the Assessment of Immune Cell Behaviour in Response to Biomaterial Implants

The Monaghan Lab at Trinity College Dublin is seeking PHD students for the Science Foundation Ireland Frontiers Grant ‘BrillFLIM’ which will employ novel imaging modalities in the assessment of immune cell behaviour in response to biomaterial implants. Specifically these modalities are Brillouin microscopy, and fluorescent lifetime imaging microscope. The researchers will work closely with other members of a multidisciplinary project team including PIs and postgraduate researchers within this research cluster. This is an innovative cutting-edge project which will yield transformative developments in the field of Biomedical Engineering. The Monaghan research group is known for their prowess in biomaterials, stem cell biology and microscopy research in Ireland and internationally. Funding is offered for 48 months. The PhD students will join on a full-time basis on a project that will involve aspects of non-invasive label-free imaging of cellular viscoelasticity and metabolism in response to engineered biomaterial substrates. The projects are highly interdisciplinary and merge the fields of biomedical engineering, advanced microscopy, computer science, biomaterials science and physics. These posts are held in the School of Engineering and Discipline of Mechanical, Manufacturing and Biomedical Engineering, Trinity College Dublin.

Qualifications

Applicants should ideally hold a primary degree in biomedical engineering, materials science, biomaterials, biomedical science, biophysics (in particular photonics/imaging). Preference will be given to candidates who have experience in biomaterials or in cell culture techniques. Specific skills that would enhance a candidate’s application for the position might include experience in some of the following areas: biomaterial synthesis and characterisation, , cell culture (in particular the culture of primary cells), mechanical testing of materials, advanced microscopy, PCR, immunohistochemistry and other histological and imaging techniques. Excellent written and oral communication skills are essential. The ideal candidate must should hold an honours undergraduate degree in a relevant discipline (e.g. materials engineering, biomedical engineering, biomedical science). There is no one ‘specific’ discipline that fits this project. Ideally an engineer/biomedical scientist. We are looking for someone that is motivated, intrigued by scientific discovery, diligent and pays attention – taking pride in their work; and overall a good team player. This is the primary criteria.

Knowledge & Experience (Essential & Desirable)

There are a number of PhD positions associated with this project, each with specific skills required and training will be provided where needed. Wet lab experience, Knowledge of biomaterials and tissue engineering, Cell culture (ideally primary cells, A keen desire to learn and become proficient in new skills,In silico modelling (COMSOL/FEA), Experience working with statistical software, e.g. GraphPad Prism, R, Experience working as a research assistant in applied settings, Experience working with qualitative and/or quantitative data, Demonstrable research interests within regenerative medicine, Proven ability to plan, prioritise and meet deadlines, Excellent communication and interpersonal skills, Ability to work independently and as part of a team, Excellent IT skills, including MS Office, e-mail and Internet. Skills & CompetenciesWhile candidates may not possess all the skills above, I still welcome applications from individuals in complimentary skills. For many of the techniques above, candidates will be expertly trained by existing members in the lab and through collaborators. It really is key that an individual is open to such training and can grasp concepts quickly.

How to make an application

Please fill out your details in the form below, and upload one single .pdf containing a cover letter, CV and additional information. Filesize limit of 600 kb. Please note that only shortlisted applicants will receive a response.